Biomarkers in DILI: One More Step Forward

Biomarkers in DILI: One More Step Forward

Despite being relatively rare, drug-induced liver injury (DILI) is a serious condition, both for the individual patient due to the risk of acute liver failure, and for the drug development industry and regulatory agencies due to associations with drug development attritions, black box warnings, and postmarketing withdrawals. A major limitation in DILI diagnosis and prediction is the current lac...

One step forward

one step forward

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Religiosity and telomere length: One step forward, one step back.

a Harvard T.H. Chan School of Public Health, Department of Epidemiology, Program on Integrative Knowledge and Human Flourishing, Harvard University, National Consortium on Psychosocial Stress, Spirituality, and Health, United States b Harvard Medical School, Harvard/MGH Center on Genomics, Vulnerable Populations, and Health Disparities, National Consortium on Psychosocial Stress, Spirituality, ...

ARDS definitions in children: one step forward.

3. Ashbaugh DG, Bigelow DB, Petty TL, Levine BE. Acute respiratory distress in adults. Lancet. 1967;290:319-23. 4. ARDS definition task force. Acute Respiratory Distress Syndrome: the Berlin definition. JAMA. 2012;307:2526-33. 5. Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A,Beale R,et al. The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material....